Tissue expression
Cell line expression
Protein structure
HBA1
Hemoglobin subunit alpha 1HBA-T3
The human alpha globin gene cluster located on chromosome 16 spans about 30 kb and includes seven loci: 5'- zeta - pseudozeta - mu - pseudoalpha-1 - alpha-2 - alpha-1 - theta - 3'. The alpha-2 (HBA2) and alpha-1 (HBA1) coding sequences are identical. These genes differ slightly over the 5' untranslated regions and the introns, but they differ significantly over the 3' untranslated regions. Two alpha chains plus two beta chains constitute HbA, which in normal adult life comprises about 97% of the total hemoglobin; alpha chains combine with delta chains to constitute HbA-2, which with HbF (fetal hemoglobin) makes up the remaining 3% of adult hemoglobin. Alpha thalassemias result from deletions of each of the alpha genes as well as deletions of both HBA2 and HBA1; some nondeletion alpha thalassemias have also been reported. [provided by RefSeq, Jul 2008]
Top validated antibodies |
|||||
Novus Biologicals | NB110-41083 | 13 references | Polyclonal |
WB
EL
ICC
ChIP |
|
antibodies-online | ABIN952707 | 5 references | Polyclonal |
WB
IHC
FC
|
|
Proteintech Group | 14537-1-AP | 10 references | Polyclonal |
WB
EL
IP
|
|
OriGene | AM33232PU-M | Monoclonal |
WB
IHC
FC
|
||
Invitrogen Antibodies | H00003039-M02 | Monoclonal |
WB
EL
OA
|
All Antibodies
Filters
Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider