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Protein structure
HNF1B
HNF1 homeobox BHNF1beta, LFB3, MODY5, TCF2, VHNF1
This gene encodes a member of the homeodomain-containing superfamily of transcription factors. The protein binds to DNA as either a homodimer, or a heterodimer with the related protein hepatocyte nuclear factor 1-alpha. The gene has been shown to function in nephron development, and regulates development of the embryonic pancreas. Mutations in this gene result in renal cysts and diabetes syndrome and noninsulin-dependent diabetes mellitus, and expression of this gene is altered in some types of cancer. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]
Top validated antibodies |
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| Invitrogen Antibodies |  720259 |
2 references | Polyclonal |
WB
ICC
FC
ChIP
OA
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| Proteintech Group | 12533-1-AP |
18 references | Polyclonal |
WB
EL
ICC
IHC
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| Atlas Antibodies | AMAb90733 |
Monoclonal |
WB
ICC
IHC
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| Novus Biologicals | NBP1-89680 |
5 references | Polyclonal |
WB
ICC
IHC
ChIP
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| Affinity Biosciences | DF10056 |
Polyclonal |
WB
EL
ICC
IHC
|
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