WH0000673M1

antibody from MilliporeSigma / Merck KGaA

Targeting: BRAF BRAF1

ELISA (Recommended by provider)

Antibody Data

Product number

WH0000673M1

Provider

MilliporeSigma / Merck KGaA

Product name

Monoclonal Anti-BRAF antibody produced in mouse

Antibody type

Monoclonal

Antigen

BRAF (NP_004324, a.a. 346-445) partial recombinant protein with GST tag. MW of the GST tag alone is 26 kDa.

Description

ascites fluid

Reactivity

Human

Antigen sequence

FRPADEDHRNQFGQRDRSSSAPNVHINTIEPVNID
DLIRDQGFRGDGGSTTGLSATPPASLPGSLTNVKA
LQKSPGPQRERKSSSSSEDRNRMKTLGRRD (wit
hout GST)


Isotype

IgM

Storage

-20C

References

Submitted references

RAF inhibitors prime wild-type RAF to activate the MAPK pathway and enhance growth

Georgia Hatzivassiliou, Kyung Song, Ivana Yen, Barbara J. Brandhuber, Daniel J. Anderson, Ryan Alvarado, Mary J. C. Ludlam, David Stokoe, Susan L. Gloor, Guy Vigers, Tony Morales, Ignacio Aliagas, Bonnie Liu, Steve Sideris, Klaus P. Hoeflich, Bijay S. Jaiswal, Somasekar Seshagiri, Hartmut Koeppen, Marcia Belvin, Lori S. Friedman, Shiva Malek
Nature 2010 Feb;464(7287):431-435