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Cell line expression
Protein structure
SOD1
Superoxide dismutase 1ALS, ALS1, IPOA
The protein encoded by this gene binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. In addition, this protein contains an antimicrobial peptide that displays antibacterial, antifungal, and anti-MRSA activity against E. coli, E. faecalis, S. aureus, S. aureus MRSA LPV+, S. agalactiae, and yeast C. krusei. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis. Rare transcript variants have been reported for this gene. [provided by RefSeq, Jul 2020]
Top validated antibodies |
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| GeneTex |  GTX100554 |
23 references | Polyclonal |
WB
EL
ICC
IHC
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| Proteintech Group | 10269-1-AP |
136 references | Polyclonal |
WB
EL
ICC
IP
IHC
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| Atlas Antibodies | HPA001401 |
2 references | Polyclonal |
WB
ICC
IHC
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| Invitrogen Antibodies | PA5-85095 |
1 references | Polyclonal |
WB
EL
ICC
IHC
OA
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| Novus Biologicals | NBP1-47443 |
7 references | Monoclonal |
WB
EL
ICC
FC
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