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Protein structure
HNRNPA1
Heterogeneous nuclear ribonucleoprotein A1ALS20, hnRNP-A1, HNRPA1
This gene encodes a member of a family of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs), which are RNA-binding proteins that associate with pre-mRNAs in the nucleus and influence pre-mRNA processing, as well as other aspects of mRNA metabolism and transport. The protein encoded by this gene is one of the most abundant core proteins of hnRNP complexes and plays a key role in the regulation of alternative splicing. Mutations in this gene have been observed in individuals with amyotrophic lateral sclerosis 20. Multiple alternatively spliced transcript variants have been found. There are numerous pseudogenes of this gene distributed throughout the genome. [provided by RefSeq, Feb 2016]
Top validated antibodies |
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| Novus Biologicals |  NB100-672 |
28 references | Monoclonal |
WB
EL
ICC
IP
IHC
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| Proteintech Group | 11176-1-AP |
18 references | Polyclonal |
WB
EL
ICC
IHC
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| Invitrogen Antibodies | PA5-19431 |
3 references | Polyclonal |
WB
ICC
IHC
OA
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| GeneTex | GTX25832 |
2 references | Monoclonal |
WB
ICC
IP
IHC
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| Cell Signaling Technology, Inc | 8443 |
1 references | Monoclonal |
WB
ICC
IP
FC
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