Explore
Validate
LearnTissue expression
Cell line expression
Protein structure
CFL2
Cofilin 2NEM7
This gene encodes an intracellular protein that is involved in the regulation of actin-filament dynamics. This protein is a major component of intranuclear and cytoplasmic actin rods. It can bind G- and F-actin in a 1:1 ratio of cofilin to actin, and it reversibly controls actin polymerization and depolymerization in a pH-dependent manner. Mutations in this gene cause nemaline myopathy type 7, a form of congenital myopathy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2009]
Top validated antibodies |
|||||
| Invitrogen Antibodies |  PA5-80472 |
Polyclonal |
WB
ICC
IP
IHC
OA
|
||
| Proteintech Group | 11848-1-AP |
1 references | Polyclonal |
WB
EL
ICC
IHC
|
|
| Novus Biologicals | H00001073-M03 |
Monoclonal |
WB
EL
ICC
IHC
|
||
| Abnova Corporation | H00001073-M03 |
Monoclonal |
WB
EL
ICC
IHC
|
||
| Atlas Antibodies | HPA045599 |
Polyclonal |
WB
ICC
IHC
|
||
All Antibodies
Filters
Enhanced validation Supportive data in Antibodypedia Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider