Tissue expression
Cell line expression
Protein structure
CFL2
Cofilin 2NEM7
This gene encodes an intracellular protein that is involved in the regulation of actin-filament dynamics. This protein is a major component of intranuclear and cytoplasmic actin rods. It can bind G- and F-actin in a 1:1 ratio of cofilin to actin, and it reversibly controls actin polymerization and depolymerization in a pH-dependent manner. Mutations in this gene cause nemaline myopathy type 7, a form of congenital myopathy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2009]
Top validated antibodies |
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LSBio | ![]() |
Polyclonal |
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Invitrogen Antibodies | ![]() |
Polyclonal |
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Proteintech Group | ![]() |
1 references | Polyclonal |
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Novus Biologicals | ![]() |
Monoclonal |
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Abnova Corporation | ![]() |
Monoclonal |
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