Tissue expression
Cell line expression
Protein structure
ACTC1
Actin alpha cardiac muscle 1ACTC, CMD1R
Actins are highly conserved proteins that are involved in various types of cell motility. Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of a two-stranded helix. Each actin can bind to four others. The protein encoded by this gene belongs to the actin family which is comprised of three main groups of actin isoforms, alpha, beta, and gamma. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. Defects in this gene have been associated with idiopathic dilated cardiomyopathy (IDC) and familial hypertrophic cardiomyopathy (FHC). [provided by RefSeq, Jul 2008]
Top validated antibodies |
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GeneTex | GTX80809 | 1 references | Monoclonal |
WB
EL
ICC
IP
IHC
ChIP |
|
Invitrogen Antibodies | 23660-1-AP | Polyclonal |
WB
ICC
IP
IHC
FC
OA |
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Proteintech Group | 66125-1-Ig | 2 references | Monoclonal |
WB
EL
ICC
IHC |
|
Novus Biologicals | NBP1-97725 | 2 references | Monoclonal |
WB
EL
ICC
IHC |
|
Abgent | AP1491a | 1 references | Polyclonal |
WB
ICC
IHC
|
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Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider