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DIABLO
Diablo IAP-binding mitochondrial proteinDFNA64, DIABLO-S, FLJ10537, FLJ25049, SMAC
This gene encodes an inhibitor of apoptosis protein (IAP)-binding protein. The encoded mitochondrial protein enters the cytosol when cells undergo apoptosis, and allows activation of caspases by binding to inhibitor of apoptosis proteins. Overexpression of the encoded protein sensitizes tumor cells to apoptosis. A mutation in this gene is associated with young-adult onset of nonsyndromic deafness-64. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2013]
Top validated antibodies |
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| Proteintech Group |  10434-1-AP |
6 references | Polyclonal |
WB
EL
ICC
IP
IHC
FC
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| Novus Biologicals | NBP1-97590 |
5 references | Monoclonal |
WB
EL
ICC
IP
IHC
FC
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| Enzo Life Sciences | ALX-804-333-C100 |
4 references | Monoclonal |
WB
EL
ICC
IP
FC
|
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| antibodies-online | ABIN393216 |
5 references | Monoclonal |
WB
EL
IHC
|
|
| Invitrogen Antibodies | 10434-1-AP |
Polyclonal |
WB
IHC
FC
OA
|
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