PTPRJ

gene product
CD148, DEP1, HPTPeta
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes, including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region containing five fibronectin type III repeats, a single transmembrane region, and a single intracytoplasmic catalytic domain, and thus represents a receptor-type PTP. This protein is present in all hematopoietic lineages, and was shown to negatively regulate T cell receptor signaling possibly through interfering with the phosphorylation of Phospholipase C Gamma 1 and Linker for Activation of T Cells. This protein can also dephosphorylate the PDGF beta receptor, and may be involved in UV-induced signal transduction. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
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Novus Biologicals
48 antibodies
R&D Systems
19 antibodies
OriGene
9 antibodies
Proteintech Group
1 antibody
antibodies-online
166 antibodies
Biorbyt
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Abgent
2 antibodies
Aviva Systems Biology
1 antibody
LifeSpan BioSciences, Inc.
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Invitrogen Antibodies
10 antibodies
Acris Antibodies GmbH
6 antibodies
GeneTex
3 antibodies
ProSci
2 antibodies
Abbkine Scientific Co.Ltd.
1 antibody
NovoPro Bioscience Inc.
4 antibodies
Abnova Corporation
2 antibodies
United States Biological
27 antibodies
MyBioSource
4 antibodies
Atlas Antibodies
1 antibody
EMD Millipore
1 antibody
Miltenyi Biotec
12 antibodies
Antibodies.com
4 antibodies
Creative Biolabs
40 antibodies
St John's Laboratory
2 antibodies
Boster Biological Technology
1 antibody
Sigma-Aldrich
4 antibodies
Creative Diagnostics
7 antibodies
Abbexa
5 antibodies
Arigo
4 antibodies
eBioscience, An Affymetrix Company
2 antibodies
Leading Biology
1 antibody