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Protein structure
COMP
Cartilage oligomeric matrix proteinEDM1, EPD1, MED, PSACH, THBS5
The protein encoded by this gene is a noncollagenous extracellular matrix (ECM) protein. It consists of five identical glycoprotein subunits, each with EGF-like and calcium-binding (thrombospondin-like) domains. Oligomerization results from formation of a five-stranded coiled coil and disulfides. Binding to other ECM proteins such as collagen appears to depend on divalent cations. Contraction or expansion of a 5 aa aspartate repeat and other mutations can cause pseudochondroplasia (PSACH) and multiple epiphyseal dysplasia (MED). [provided by RefSeq, Jul 2016]
Top validated antibodies |
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| LSBio |  LS-C166937 |
Polyclonal |
WB
EL
IHC
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| Invitrogen Antibodies | PA5-95547 |
Polyclonal |
WB
EL
ICC
IHC
FC
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| Boster Biological Technology | A02443-1 |
Polyclonal |
WB
EL
ICC
IHC
FC
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| GeneTex | GTX11056 |
1 references | Monoclonal |
WB
EL
IP
IHC
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| antibodies-online | ABIN2030103 |
Polyclonal |
WB
EL
IHC
FC
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