POLR3K

This gene encodes a small essential subunit of RNA polymerase III, the polymerase responsible for synthesizing transfer and small ribosomal RNAs in eukaryotes. The carboxy-terminal domain of this subunit shares a high degree of sequence similarity to the carboxy-terminal domain of an RNA polymerase II elongation factor. This similarity in sequence is supported by functional studies showing that this subunit is required for proper pausing and termination during transcription. Pseudogenes of this gene are found on chromosomes 13 and 17. [provided by RefSeq, Jul 2010]

Description

RNA polymerase III subunit K

Tissue specificity

Low tissue specificity

Subcell location

Nucleoplasm, Cytosol

Predicted location

Intracellular

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Metabolic proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
RNA polymerase related proteins

Chromosome

16 (46407 - 53608)

Ensembl ID

ENSG00000161980  (ver. 103.38)

Orthologs

Mouse Polr3k: ENSMUSG00000038628

UniProt

Q9Y2Y1

neXtProt

NX_Q9Y2Y1

Human splice variants
Mouse splice variants

Protein structure