Tissue expression
Cell line expression
Protein structure
TSPAN8
Tetraspanin 8CO-029, TM4SF3
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. This gene is expressed in different carcinomas. The use of alternate polyadenylation sites has been found for this gene. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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| Invitrogen Antibodies | 1 references | Monoclonal |
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| NSJ Bioreagents | Polyclonal |
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| Novus Biologicals | 1 references | Monoclonal |
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| Boster Biological Technology | Polyclonal |
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| Antibodies.com | Polyclonal |
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