Tissue expression
Cell line expression
Protein structure
IMPDH2
Inosine monophosphate dehydrogenase 2This gene encodes the rate-limiting enzyme in the de novo guanine nucleotide biosynthesis. It is thus involved in maintaining cellular guanine deoxy- and ribonucleotide pools needed for DNA and RNA synthesis. The encoded protein catalyzes the NAD-dependent oxidation of inosine-5'-monophosphate into xanthine-5'-monophosphate, which is then converted into guanosine-5'-monophosphate. This gene is up-regulated in some neoplasms, suggesting it may play a role in malignant transformation. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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Proteintech Group | 12948-1-AP | 31 references | Polyclonal |
WB
EL
ICC
IP
IHC
|
|
Atlas Antibodies | HPA001400 | 4 references | Polyclonal |
WB
ICC
IHC
|
|
antibodies-online | ABIN395050 | 5 references | Monoclonal |
WB
EL
IP
IHC |
|
Invitrogen Antibodies | 12948-1-AP | Polyclonal |
WB
ICC
IP
IHC
OA
|
||
Novus Biologicals | NBP2-75541 | Monoclonal |
WB
ICC
IP
IHC
FC
|
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Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
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Recommended by provider
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider