RTKN

gene product
B5
This gene encodes a scaffold protein that interacts with GTP-bound Rho proteins. Binding of this protein inhibits the GTPase activity of Rho proteins. This protein may interfere with the conversion of active, GTP-bound Rho to the inactive GDP-bound form by RhoGAP. Rho proteins regulate many important cellular processes, including cytokinesis, transcription, smooth muscle contraction, cell growth and transformation. Dysregulation of the Rho signal transduction pathway has been implicated in many forms of cancer. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
More gene data

Featured antibodies

Antibodies

 

Filters

Application

Antibodypedia Validation Initiative

Validation method

Reference

Provider

Host

Reactivity

Antibody type

Conjugate

Antibody

  or   Clear
Enhanced validation
Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Validated within AVI
Eligible for validation within AVI
240 antibodies from 28 providers.

Antibody properties

General

Applications

or Cancel
Antibody
Novus Biologicals
27 antibodies
Invitrogen Antibodies
6 antibodies
antibodies-online
64 antibodies
OriGene
27 antibodies
LifeSpan BioSciences, Inc.
41 antibodies
Biorbyt
11 antibodies
Abnova Corporation
3 antibodies
GeneTex
2 antibodies
Acris Antibodies GmbH
1 antibody
Atlas Antibodies
1 antibody
Proteintech Group
1 antibody
Bioworld Technology, Inc
2 antibodies
NovoPro Bioscience Inc.
4 antibodies
Abgent
3 antibodies
St John's Laboratory
3 antibodies
Affinity Biosciences
1 antibody
Aviva Systems Biology
2 antibodies
ProSci
1 antibody
United States Biological
14 antibodies
Creative Biolabs
6 antibodies
Creative Diagnostics
5 antibodies
MyBioSource
4 antibodies
Boster Biological Technology
1 antibody
RabMAbs
1 antibody
RayBiotech, Inc.
1 antibody
Leading Biology
3 antibodies
Sigma-Aldrich
4 antibodies
Abbkine Scientific Co.Ltd.
1 antibody