Explore
Validate
LearnTissue expression
Cell line expression
Protein structure
NLRP12
NLR family pyrin domain containing 12CLR19.3, Monarch1, NALP12, PAN6, PYPAF7, RNO2
This gene encodes a member of the CATERPILLER family of cytoplasmic proteins. The encoded protein, which contains an N-terminal pyrin domain, a NACHT domain, a NACHT-associated domain, and a C-terminus leucine-rich repeat region, functions as an attenuating factor of inflammation by suppressing inflammatory responses in activated monocytes. Mutations in this gene cause familial cold autoinflammatory syndrome type 2. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2013]
Top validated antibodies |
|||||
| Novus Biologicals |  NBP1-76293 |
1 references | Polyclonal |
WB
EL
ICC
IHC
|
|
| Invitrogen Antibodies | PA5-21027 |
1 references | Polyclonal |
WB
IHC
OA
|
|
| GeneTex | GTX31418 |
Polyclonal |
WB
EL
ICC
IHC
|
||
| Boster Biological Technology | A02124 |
Polyclonal |
WB
EL
ICC
IHC
|
||
| antibodies-online | ABIN2449035 |
Polyclonal |
WB
EL
ICC
IHC
|
||
All Antibodies
Filters
Enhanced validation Supportive data in Antibodypedia Data presented on provider website
Data in Antibodypedia (inconclusive) Recommended by provider