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Protein structure
IL37
Interleukin 37FIL1, FIL1(ZETA), FIL1Z, IL-1F7, IL-1H4, IL-1RP1, IL1F7
The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine can bind to, and may be a ligand for interleukin 18 receptor (IL18R1/IL-1Rrp). This cytokine also binds to interleukin 18 binding protein (IL18BP), an inhibitory binding protein of interleukin 18 (IL18), and subsequently forms a complex with IL18 receptor beta subunit, and through which it inhibits the activity of IL18. This gene along with eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. Five alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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| Proteintech Group |  60296-1-Ig |
4 references | Monoclonal |
WB
EL
IHC
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| Novus Biologicals | NBP2-14992 |
1 references | Polyclonal |
WB
ICC
IHC
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| Invitrogen Antibodies | PA5-115405 |
1 references | Polyclonal |
WB
IHC
OA
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| LSBio | LS-B10134 |
Polyclonal |
WB
EL
ICC
IHC
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| NSJ Bioreagents | RQ6257 |
Polyclonal |
EL
ICC
IHC
FC
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