PARP1

Poly(ADP-ribose) polymerase 1

ADPRT, ARTD1, PARP, PPOL

This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes. [provided by RefSeq, Jul 2008]

Ensembl	UniProt	RefSeq	Entrez
ENST00000366794 ENSP00000355759	P09874.249 P09874 A0A024R3T8	NP_001609.2 NP_001609	PARP1 142
ENST00000677203 ENSP00000503396			PARP1 142

Ensembl	UniProt	RefSeq	Entrez
ENSMUST00000027777 ENSMUSP00000027777	Q921K2	NP_031441.2 NP_031441	Parp1 11545
ENSMUST00000194434 ENSMUSP00000141775	A0A0A6YX03		Parp1 11545
ENSMUST00000194608 ENSMUSP00000142295	A0A0A6YY63		Parp1 11545
ENSMUST00000195560 ENSMUSP00000141301	A0A0A6YVX0		Parp1 11545

More gene data

Top validated antibodies
GeneTex	GTX100573	40 references	Polyclonal	WB ICC IP IHC ChIP
Invitrogen Antibodies	436400	9 references	Monoclonal	WB ICC IP IHC FC OA
Proteintech Group	13371-1-AP	322 references	Polyclonal	WB EL ICC IP IHC FC
Atlas Antibodies	HPA045168		Polyclonal	WB ICC IHC
antibodies-online	ABIN394297	5 references	Monoclonal	WB EL ICC IHC

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	Antibody	Refs	Type
GeneTex 23 antibodies
	GTX100573	40	Polyclonal
	GTX112864	4	Polyclonal

Invitrogen Antibodies 93 antibodies
	436400	9	Monoclonal
	PA5-34802	1	Polyclonal

Proteintech Group 9 antibodies
	13371-1-AP	322	Polyclonal
	66520-1-Ig	31	Monoclonal

Atlas Antibodies 3 antibodies
	HPA045168		Polyclonal
	AMAb90959		Monoclonal

antibodies-online 571 antibodies
	ABIN394297	5	Monoclonal
	ABIN2869486	3	Monoclonal

Abnova Corporation 17 antibodies
	H00000142-M01	6	Monoclonal
	MAB0097	5	Monoclonal

Bioss 18 antibodies
	bs-2138R	5	Polyclonal
	bsm-52433R		Monoclonal

Novus Biologicals 36 antibodies
	AF-600-NA	4	Polyclonal
	NB100-56599	9	Monoclonal

Cell Signaling Technology, Inc 16 antibodies
	9532	2	Monoclonal
	32563		Monoclonal

R&D Systems 6 antibodies
	AF-600-NA	3	Polyclonal
	4338-MC-50	2	Monoclonal

NSJ Bioreagents 18 antibodies
	RQ6271		Monoclonal
	RQ6272		Monoclonal

Biorbyt 172 antibodies
	orb1274565		Polyclonal
	orb689071		Monoclonal

Boster Biological Technology 10 antibodies
	A00122		Polyclonal
	M00122-4		Monoclonal

OriGene 27 antibodies
	TA804938	1	Monoclonal
	TA804938S	1	Monoclonal

Enzo Life Sciences 8 antibodies
	ALX-210-302-R100	3	Polyclonal
	BML-SA249-0050	16	Monoclonal

Cusabio Biotech Co., Ltd 19 antibodies
	CSB-RA581794A0HU		Recombinant
	CSB-PA017457LA01HU		Polyclonal

St John's Laboratory 15 antibodies
	STJ29827		Polyclonal
	STJ90100		Polyclonal

Abgent 29 antibodies
	AJ1588a	1	Monoclonal
	AP6373A		Polyclonal

HUABIO Research 4 antibodies
	EM1701-16		Monoclonal
	ET1608-10		Monoclonal

Wuhan Fine Biotech Co., Ltd. 3 antibodies
	FNab06151		Polyclonal
	FNab09939		Monoclonal

LSBio 404 antibodies
	LS-C288177		Polyclonal
	LS-C285949		Polyclonal

Acris Antibodies GmbH 24 antibodies
	SM7016A	4	Monoclonal
	SM7016P	4	Monoclonal

BioLegend 9 antibodies
	669901		Recombinant
	669902		Recombinant

Arigo 7 antibodies
	ARG20432		Monoclonal
	ARG20434		Monoclonal

NovoPro Bioscience Inc. 10 antibodies
	113587		Polyclonal
	113588		Polyclonal

Affinity Biosciences 4 antibodies
	DF7198		Polyclonal
	AF7023		Polyclonal

Bethyl Laboratories 3 antibodies
	A301-376A		Polyclonal
	A301-375A		Polyclonal

ProSci 12 antibodies
	62-267		Polyclonal
	49-051		Monoclonal

RabMAbs 16 antibodies
	1051-1		Monoclonal
	1072-1		Monoclonal

Abbkine Scientific Co.Ltd. 7 antibodies
	ABP59832		Polyclonal
	ABP50053		Polyclonal

Aviva Systems Biology 17 antibodies
	OAAB03468		Polyclonal
	OAAF05400		Polyclonal

MyBioSource 30 antibodies
	MBS273960		Polyclonal
	MBS840142		Monoclonal

Creative Diagnostics 11 antibodies
	CABT-50340MP		Monoclonal
	CAB-7545RH		Monoclonal

Creative Biolabs 45 antibodies
	CBMAB-CP1868-LY		Recombinant
	MOB-1732z-F(E)		Monoclonal

Bioworld Technology, Inc 3 antibodies
	BS70001		Polyclonal
	BS7045		Polyclonal

United States Biological 228 antibodies
	P3113-22		Monoclonal
	207324		Polyclonal

RayBiotech, Inc. 9 antibodies
	119-13693		Monoclonal
	168-10001		Monoclonal

GenWay 11 antibodies
	20-783-70611		Monoclonal
	20-272-191047		Monoclonal

EMD Millipore 8 antibodies
	04-576		Monoclonal
	04-575		Monoclonal

Abbiotec 2 antibodies
	251279		Polyclonal
	252976		Monoclonal

Rockland Immunochemicals, Inc. 1 antibody
	200-301-I03		Monoclonal

Abbexa 32 antibodies
	abx016081		Monoclonal
	abx128898		Polyclonal

Leading Biology 27 antibodies
	APR07143G		Monoclonal
	APR08930G		Monoclonal

Spring Bioscience 4 antibodies
	E4220		Polyclonal
	E4221		Polyclonal

Abiocode, Inc. 3 antibodies
	R0191-1		Polyclonal
	R0191-2		Polyclonal

MilliporeSigma / Merck KGaA 10 antibodies
	SAB1403527		Monoclonal
	WH0000142M1		Monoclonal

Active Motif 2 antibodies
	39559		Polyclonal
	39561		Polyclonal

eBioscience, An Affymetrix Company 9 antibodies
	14-6666-92		Monoclonal
	14-6667-80		Monoclonal

Sino Biological Inc. 3 antibodies
	11040-MM04		Monoclonal
	11040-RP01		Polyclonal

CPTAC 2 antibodies
	CPTC-PARP1-1		Monoclonal
	CPTC-PARP1-2		Monoclonal

PARP1

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PARP1

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