Tissue expression
Cell line expression
Protein structure
GLI2
GLI family zinc finger 2HPE9, THP1, THP2
This gene encodes a protein which belongs to the C2H2-type zinc finger protein subclass of the Gli family. Members of this subclass are characterized as transcription factors which bind DNA through zinc finger motifs. These motifs contain conserved H-C links. Gli family zinc finger proteins are mediators of Sonic hedgehog (Shh) signaling and they are implicated as potent oncogenes in the embryonal carcinoma cell. The protein encoded by this gene localizes to the cytoplasm and activates patched Drosophila homolog (PTCH) gene expression. It is also thought to play a role during embryogenesis. The encoded protein is associated with several phenotypes- Greig cephalopolysyndactyly syndrome, Pallister-Hall syndrome, preaxial polydactyly type IV, postaxial polydactyly types A1 and B. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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Novus Biologicals | NB600-874 | 6 references | Polyclonal |
WB
EL
IHC
FC
ChIP
|
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Proteintech Group | 18989-1-AP | 29 references | Polyclonal |
WB
EL
ICC
IHC |
|
NSJ Bioreagents | RQ8264 | Polyclonal |
WB
EL
ICC
IHC
FC
|
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antibodies-online | ABIN269891 | 3 references | Polyclonal |
WB
EL
IHC
FC
ChIP
|
|
GeneTex | GTX27195 | 3 references | Polyclonal |
WB
EL
IHC
|
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Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider