Explore
Validate
LearnTissue expression
Cell line expression
Protein structure
HGF
Hepatocyte growth factorDFNB39, F-TCF, HGFB, HPTA, SF
This gene encodes a protein that binds to the hepatocyte growth factor receptor to regulate cell growth, cell motility and morphogenesis in numerous cell and tissue types. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate alpha and beta chains, which form the mature heterodimer. This protein is secreted by mesenchymal cells and acts as a multi-functional cytokine on cells of mainly epithelial origin. This protein also plays a role in angiogenesis, tumorogenesis, and tissue regeneration. Although the encoded protein is a member of the peptidase S1 family of serine proteases, it lacks peptidase activity. Mutations in this gene are associated with nonsyndromic hearing loss. [provided by RefSeq, Nov 2015]
Top validated antibodies |
|||||
| Invitrogen Antibodies |  701283 |
2 references | Monoclonal |
WB
ICC
FC
OA
|
|
| R&D Systems | AF-294-NA |
21 references | Polyclonal |
WB
IHC
BN
|
|
| Novus Biologicals | AF-294-NA |
21 references | Polyclonal |
WB
IHC
BN
|
|
| Proteintech Group | 26881-1-AP |
11 references | Polyclonal |
WB
EL
IHC
|
|
| antibodies-online | ABIN2848889 |
7 references | Polyclonal |
WB
IHC
FC
|
|
All Antibodies
Filters
Enhanced validation Supportive data in Antibodypedia Data presented on provider website
Data in Antibodypedia (inconclusive) Recommended by provider