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Protein structure
TXNIP
Thioredoxin interacting proteinARRDC6, EST01027, HHCPA78, THIF, VDUP1
This gene encodes a thioredoxin-binding protein that is a member of the alpha arrestin protein family. Thioredoxin is a thiol-oxidoreductase that is a major regulator of cellular redox signaling which protects cells from oxidative stress. This protein inhibits the antioxidative function of thioredoxin resulting in the accumulation of reactive oxygen species and cellular stress. This protein also functions as a regulator of cellular metabolism and of endoplasmic reticulum (ER) stress. This protein may also function as a tumor suppressor. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]
Top validated antibodies |
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| Novus Biologicals |  NBP1-54578 |
17 references | Monoclonal |
WB
IP
IHC
FC
PLA
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| Invitrogen Antibodies | MA5-32771 |
1 references | Monoclonal |
WB
ICC
IHC
FC
OA
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| Proteintech Group | 18243-1-AP |
38 references | Polyclonal |
WB
EL
ICC
IHC
|
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| NovoPro Bioscience Inc. | 116454 |
Polyclonal |
WB
EL
ICC
IP
IHC
|
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| NSJ Bioreagents | RQ6014 |
Polyclonal |
WB
EL
IHC
FC
|
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