Tissue expression
Cell line expression
Protein structure

PMEL

Premelanosome protein
D12S53E, gp100, Pmel17, SI, SIL, SILV 
This gene encodes a melanocyte-specific type I transmembrane glycoprotein. The encoded protein is enriched in melanosomes, which are the melanin-producing organelles in melanocytes, and plays an essential role in the structural organization of premelanosomes. This protein is involved in generating internal matrix fibers that define the transition from Stage I to Stage II melanosomes. This protein undergoes a complex pattern of prosttranslational processing and modification that is essential to the proper functioning of the protein. A secreted form of this protein that is released by proteolytic ectodomain shedding may be used as a melanoma-specific serum marker. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2011]
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1328 antibodies from 40 providers.

Antibody properties

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AntibodyRefsTypeWBELICCIPIHCFC
Novus Biologicals
226 antibodies
Invitrogen Antibodies
84 antibodies
OriGene
44 antibodies
NovoPro Bioscience Inc.
6 antibodies
Abgent
6 antibodies
Biorbyt
153 antibodies
GeneTex
14 antibodies
NSJ Bioreagents
15 antibodies
Affinity Biosciences
1 antibody
Atlas Antibodies
1 antibody
Acris Antibodies GmbH
19 antibodies
antibodies-online
463 antibodies
Everest Biotech
1 antibody
St John's Laboratory
2 antibodies
Cusabio Biotech Co., Ltd
4 antibodies
Abnova Corporation
17 antibodies
Aviva Systems Biology
4 antibodies
Boster Biological Technology
3 antibodies
ProSci
4 antibodies
Proteintech Group
2 antibodies
Antibodies.com
1 antibody
Bioworld Technology, Inc
1 antibody
United States Biological
39 antibodies
Arigo
4 antibodies
Leading Biology
19 antibodies
Creative Biolabs
63 antibodies
MyBioSource
9 antibodies
RabMAbs
3 antibodies
Spring Bioscience
4 antibodies
Exalpha Biologicals, Inc.
2 antibodies
Cell Signaling Technology, Inc
1 antibody
DB Biotech
1 antibody
MS Validated Antibodies GmbH
1 antibody
Creative Diagnostics
7 antibodies
MilliporeSigma / Merck KGaA
4 antibodies
Abbexa
8 antibodies
GenWay
3 antibodies
DIMA
1 antibody
RayBiotech, Inc.
1 antibody