Tissue expression
Cell line expression
Protein structure

DYRK1A

Dual specificity tyrosine phosphorylation regulated kinase 1A
DYRK, DYRK1, MNBH 
This gene encodes a member of the Dual-specificity tyrosine phosphorylation-regulated kinase (DYRK) family. This member contains a nuclear targeting signal sequence, a protein kinase domain, a leucine zipper motif, and a highly conservative 13-consecutive-histidine repeat. It catalyzes its autophosphorylation on serine/threonine and tyrosine residues. It may play a significant role in a signaling pathway regulating cell proliferation and may be involved in brain development. This gene is a homolog of Drosophila mnb (minibrain) gene and rat Dyrk gene. It is localized in the Down syndrome critical region of chromosome 21, and is considered to be a strong candidate gene for learning defects associated with Down syndrome. Alternative splicing of this gene generates several transcript variants differing from each other either in the 5' UTR or in the 3' coding region. These variants encode at least five different isoforms. [provided by RefSeq, Jul 2008]
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422 antibodies from 38 providers.

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AntibodyRefsTypeWBELICCIPIHCFC
Novus Biologicals
5 antibodies
Abnova Corporation
6 antibodies
antibodies-online
139 antibodies
Boster Biological Technology
3 antibodies
Invitrogen Antibodies
22 antibodies
Cusabio Biotech Co., Ltd
1 antibody
R&D Systems
1 antibody
GeneTex
4 antibodies
OriGene
8 antibodies
St John's Laboratory
9 antibodies
Cell Signaling Technology, Inc
2 antibodies
Everest Biotech
1 antibody
Affinity Biosciences
3 antibodies
Aviva Systems Biology
6 antibodies
NovoPro Bioscience Inc.
3 antibodies
Acris Antibodies GmbH
9 antibodies
Bioworld Technology, Inc
1 antibody
Exalpha Biologicals, Inc.
1 antibody
SignalChem
1 antibody
Atlas Antibodies
2 antibodies
Abgent
5 antibodies
NSJ Bioreagents
4 antibodies
Abbkine Scientific Co.Ltd.
2 antibodies
Bethyl Laboratories
2 antibodies
ProSci
3 antibodies
Antibodies.com
1 antibody
RabMAbs
1 antibody
Abbexa
8 antibodies
United States Biological
63 antibodies
MyBioSource
7 antibodies
Creative Diagnostics
5 antibodies
Leading Biology
5 antibodies
MilliporeSigma / Merck KGaA
5 antibodies
Creative Biolabs
5 antibodies
Abbiotec
1 antibody
EMD Millipore
1 antibody
Rockland Immunochemicals, Inc.
1 antibody