A2M

gene product
CPAMD5, FWP007, S863-7
The protein encoded by this gene is a protease inhibitor and cytokine transporter. It uses a bait-and-trap mechanism to inhibit a broad spectrum of proteases, including trypsin, thrombin and collagenase. It can also inhibit inflammatory cytokines, and it thus disrupts inflammatory cascades. Mutations in this gene are a cause of alpha-2-macroglobulin deficiency. This gene is implicated in Alzheimer's disease (AD) due to its ability to mediate the clearance and degradation of A-beta, the major component of beta-amyloid deposits. A related pseudogene, which is also located on the p arm of chromosome 12, has been identified. [provided by RefSeq, Nov 2016]
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893 antibodies from 37 providers.

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Antibody
Proteintech Group
4 antibodies
R&D Systems
4 antibodies
Novus Biologicals
34 antibodies
NovoPro Bioscience Inc.
2 antibodies
OriGene
13 antibodies
Atlas Antibodies
1 antibody
GeneTex
13 antibodies
Abnova Corporation
14 antibodies
antibodies-online
263 antibodies
LifeSpan BioSciences, Inc.
220 antibodies
Invitrogen Antibodies
11 antibodies
Affinity Biosciences
2 antibodies
Santa Cruz Biotechnology
1 antibody
Acris Antibodies GmbH
26 antibodies
Aviva Systems Biology
7 antibodies
Bioworld Technology, Inc
2 antibodies
Abbkine Scientific Co.Ltd.
2 antibodies
Biorbyt
37 antibodies
Rockland Immunochemicals, Inc.
10 antibodies
Creative Biolabs
38 antibodies
St John's Laboratory
4 antibodies
Antibodies.com
1 antibody
Boster Biological Technology
1 antibody
NSJ Bioreagents
4 antibodies
MyBioSource
26 antibodies
Abgent
6 antibodies
RayBiotech, Inc.
4 antibodies
RabMAbs
5 antibodies
GenWay
16 antibodies
Leading Biology
6 antibodies
ProSci
5 antibodies
United States Biological
79 antibodies
Creative Diagnostics
9 antibodies
Sigma-Aldrich
3 antibodies
Green Mountain Antibodies
1 antibody
Abbexa
3 antibodies