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Protein structure
SH3BP2
SH3 domain binding protein 2CRBM, RES4-23
The protein encoded by this gene has an N-terminal pleckstrin homology (PH) domain, an SH3-binding proline-rich region, and a C-terminal SH2 domain. The protein binds to the SH3 domains of several proteins including the ABL1 and SYK protein tyrosine kinases , and functions as a cytoplasmic adaptor protein to positively regulate transcriptional activity in T, natural killer (NK), and basophilic cells. Mutations in this gene result in cherubism. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
Top validated antibodies |
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| Novus Biologicals |  H00006452-M01 |
1 references | Monoclonal |
WB
EL
ICC
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| antibodies-online | ABIN562859 |
1 references | Monoclonal |
WB
EL
ICC
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| Abnova Corporation | H00006452-M01 |
Monoclonal |
WB
EL
ICC
|
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| Atlas Antibodies | HPA036790 |
Polyclonal |
WB
ICC
IHC
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| Invitrogen Antibodies | PA5-57818 |
Polyclonal |
WB
ICC
IHC
|
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