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Protein structure
ARNT
Aryl hydrocarbon receptor nuclear translocatorbHLHe2, HIF-1beta
This gene encodes a protein containing a basic helix-loop-helix domain and two characteristic PAS domains along with a PAC domain. The encoded protein binds to ligand-bound aryl hydrocarbon receptor and aids in the movement of this complex to the nucleus, where it promotes the expression of genes involved in xenobiotic metabolism. This protein is also a co-factor for transcriptional regulation by hypoxia-inducible factor 1. Chromosomal translocation of this locus with the ETV6 (ets variant 6) gene on chromosome 12 have been described in leukemias. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2013]
Top validated antibodies |
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| Novus Biologicals |  NB100-110 |
52 references | Polyclonal |
WB
ICC
IP
IHC
GS
ChIP
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| GeneTex | GTX22771 |
7 references | Monoclonal |
WB
ICC
IP
IHC
GS
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| Proteintech Group | 14105-1-AP |
10 references | Polyclonal |
WB
EL
ICC
IP
IHC
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| antibodies-online | ABIN394250 |
5 references | Monoclonal |
WB
EL
ICC
IHC
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| Invitrogen Antibodies | MA1-16512 |
2 references | Monoclonal |
WB
ICC
IP
IHC
GS
ChIP
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