Tissue expression
Cell line expression
Protein structure
BIRC2
Baculoviral IAP repeat containing 2API1, c-IAP1, cIAP1, hiap-2, MIHB, RNF48
The protein encoded by this gene is a member of a family of proteins that inhibits apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. This encoded protein inhibits apoptosis induced by serum deprivation and menadione, a potent inducer of free radicals. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]
Top validated antibodies |
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Proteintech Group | ![]() |
19 references | Polyclonal |
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Novus Biologicals | ![]() |
2 references | Polyclonal |
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LSBio | ![]() |
Polyclonal |
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R&D Systems | ![]() |
36 references | Polyclonal |
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Enzo Life Sciences | ![]() |
12 references | Monoclonal |
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