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Protein structure
CFL1
Cofilin 1CFL
The protein encoded by this gene can polymerize and depolymerize F-actin and G-actin in a pH-dependent manner. Increased phosphorylation of this protein by LIM kinase aids in Rho-induced reorganization of the actin cytoskeleton. Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner. It is involved in the translocation of actin-cofilin complex from cytoplasm to nucleus. [supplied by OMIM, Apr 2004]
Top validated antibodies |
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| GeneTex |  GTX102156 |
12 references | Polyclonal |
WB
ICC
IHC
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| Novus Biologicals | H00001072-M04 |
4 references | Monoclonal |
WB
EL
ICC
IHC
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| Proteintech Group | 10960-1-AP |
14 references | Polyclonal |
WB
EL
ICC
IHC
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| antibodies-online | ABIN394735 |
5 references | Monoclonal |
WB
EL
ICC
IHC
|
|
| Abnova Corporation | H00001072-M04 |
3 references | Monoclonal |
WB
EL
ICC
IHC
|
|
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