KCNH6

Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily H. This member is a pore-forming (alpha) subunit. Alternative splicing results in multiple transcript variants that encode different isoforms. [provided by RefSeq, Jul 2013]

Description

Potassium voltage-gated channel subfamily H member 6

Tissue specificity

Tissue enhanced (intestine, kidney, pituitary gland, prostate, retina)

Predicted location

Membrane

Protein family

FDA approved drug targets
Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted membrane proteins
Voltage-gated ion channels

Chromosome

17 (63523334 - 63548977)

Ensembl ID

ENSG00000173826  (ver. 103.38)

Orthologs

Mouse Kcnh6: ENSMUSG00000001901

UniProt

Q9H252

neXtProt

NX_Q9H252

Human splice variants
Mouse splice variants

Protein structure