Tissue expression
Cell line expression
Protein structure
DNM1
Dynamin 1DNM
This gene encodes a member of the dynamin subfamily of GTP-binding proteins. The encoded protein possesses unique mechanochemical properties used to tubulate and sever membranes, and is involved in clathrin-mediated endocytosis and other vesicular trafficking processes. Actin and other cytoskeletal proteins act as binding partners for the encoded protein, which can also self-assemble leading to stimulation of GTPase activity. More than sixty highly conserved copies of the 3' region of this gene are found elsewhere in the genome, particularly on chromosomes Y and 15. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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Invitrogen Antibodies | PA1-660 | 22 references | Polyclonal |
WB
ICC
FC
OA |
|
Proteintech Group | 18205-1-AP | 4 references | Polyclonal |
WB
EL
ICC
IP
IHC
|
|
Boster Biological Technology | A02536-2 | Polyclonal |
WB
EL
ICC
IHC
FC
|
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Novus Biologicals | NB110-60491 | Monoclonal |
WB
EL
IHC
FC |
||
Biorbyt | orb402275 | Polyclonal |
WB
EL
ICC
IHC
FC
|
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