Tissue expression
Cell line expression

UBE3A

gene product
ANCR, AS, E6-AP, EPVE6AP, FLJ26981, HPVE6A 
This gene encodes an E3 ubiquitin-protein ligase, part of the ubiquitin protein degradation system. This imprinted gene is maternally expressed in brain and biallelically expressed in other tissues. Maternally inherited deletion of this gene causes Angelman Syndrome, characterized by severe motor and intellectual retardation, ataxia, hypotonia, epilepsy, absence of speech, and characteristic facies. The protein also interacts with the E6 protein of human papillomavirus types 16 and 18, resulting in ubiquitination and proteolysis of tumor protein p53. Alternative splicing of this gene results in three transcript variants encoding three isoforms with different N-termini. Additional transcript variants have been described, but their full length nature has not been determined. [provided by RefSeq, Jul 2008]
More gene data

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437 antibodies from 36 providers.

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AntibodyRefsTypeWBELICCIPIHCFC
Proteintech Group
2 antibodies
antibodies-online
127 antibodies
Novus Biologicals
25 antibodies
Abnova Corporation
5 antibodies
LifeSpan BioSciences, Inc.
65 antibodies
NSJ Bioreagents
4 antibodies
Abgent
3 antibodies
Biorbyt
18 antibodies
NovoPro Bioscience Inc.
2 antibodies
Invitrogen Antibodies
19 antibodies
Boster Biological Technology
5 antibodies
Aviva Systems Biology
5 antibodies
Atlas Antibodies
2 antibodies
ProSci
1 antibody
Cusabio Biotech Co., Ltd
5 antibodies
Wuhan Fine Biotech Co., Ltd.
1 antibody
GeneTex
5 antibodies
Acris Antibodies GmbH
6 antibodies
OriGene
1 antibody
Bethyl Laboratories
2 antibodies
Bioworld Technology, Inc
1 antibody
RabMAbs
3 antibodies
MilliporeSigma / Merck KGaA
7 antibodies
Creative Diagnostics
3 antibodies
United States Biological
32 antibodies
MyBioSource
6 antibodies
Abiocode, Inc.
3 antibodies
Abbexa
10 antibodies
Creative Biolabs
44 antibodies
Leading Biology
2 antibodies
Cell Signaling Technology, Inc
1 antibody
GenWay
3 antibodies
EMD Millipore
1 antibody
RayBiotech, Inc.
1 antibody
Enzo Life Sciences
2 antibodies