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Protein structure
HAVCR2
Hepatitis A virus cellular receptor 2CD366, FLJ14428, Tim-3, TIM3, TIMD3
The protein encoded by this gene belongs to the immunoglobulin superfamily, and TIM family of proteins. CD4-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas, Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. This protein is a Th1-specific cell surface protein that regulates macrophage activation, and inhibits Th1-mediated auto- and alloimmune responses, and promotes immunological tolerance. [provided by RefSeq, Sep 2011]
Top validated antibodies |
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| LSBio |  LS-C759798 |
Monoclonal |
WB
EL
ICC
IHC
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| GeneTex | GTX54054 |
7 references | Monoclonal |
ICC
IHC
FC
FA
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| R&D Systems | AF2365 |
15 references | Polyclonal |
WB
IHC
FC
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| Novus Biologicals | AF2365 |
15 references | Polyclonal |
WB
IHC
FC
|
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| Proteintech Group | 60355-1-Ig |
18 references | Monoclonal |
WB
EL
FC
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