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FH
Fumarate hydrataseThe protein encoded by this gene is an enzymatic component of the tricarboxylic acid (TCA) cycle, or Krebs cycle, and catalyzes the formation of L-malate from fumarate. It exists in both a cytosolic form and an N-terminal extended form, differing only in the translation start site used. The N-terminal extended form is targeted to the mitochondrion, where the removal of the extension generates the same form as in the cytoplasm. It is similar to some thermostable class II fumarases and functions as a homotetramer. Mutations in this gene can cause fumarase deficiency and lead to progressive encephalopathy. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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| Proteintech Group |  10966-1-AP |
2 references | Polyclonal |
WB
EL
ICC
IP
IHC
FC
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| Invitrogen Antibodies | 10966-1-AP |
Polyclonal |
WB
ICC
IP
IHC
FC
OA
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| GeneTex | GTX110128 |
2 references | Polyclonal |
WB
ICC
IHC
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| NovoPro Bioscience Inc. | 110646 |
Polyclonal |
WB
EL
ICC
IP
IHC
FC
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| Wuhan Fine Biotech Co., Ltd. | FNab03106 |
Polyclonal |
WB
EL
ICC
IP
IHC
FC
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