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Protein structure
ICAM3
Intercellular adhesion molecule 3CD50, CDW50, ICAM-R
The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein is constitutively and abundantly expressed by all leucocytes and may be the most important ligand for LFA-1 in the initiation of the immune response. It functions not only as an adhesion molecule, but also as a potent signalling molecule. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Feb 2016]
Top validated antibodies |
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| OriGene |  AM33033PU-N |
Monoclonal |
WB
EL
ICC
IP
IHC
FC
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| Novus Biologicals | NB100-2609 |
Monoclonal |
WB
EL
ICC
IP
IHC
FC
RA
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| R&D Systems | BBA15 |
1 references | Monoclonal |
WB
EL
ICC
IP
FC
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| Invitrogen Antibodies | 17699-1-AP |
Polyclonal |
WB
IP
IHC
FC
OA
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| Proteintech Group | 17699-1-AP |
Polyclonal |
WB
EL
IP
IHC
FC
|
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