OLIG2
gene productBHLHB1, bHLHe19, OLIGO2, PRKCBP2, RACK17
This gene encodes a basic helix-loop-helix transcription factor which is expressed in oligodendroglial tumors of the brain. The protein is an essential regulator of ventral neuroectodermal progenitor cell fate. The gene is involved in a chromosomal translocation t(14;21)(q11.2;q22) associated with T-cell acute lymphoblastic leukemia. Its chromosomal location is within a region of chromosome 21 which has been suggested to play a role in learning deficits associated with Down syndrome. [provided by RefSeq, Jul 2008]
Featured antibodies
 Biorbyt |
 orb69381 |
0 references | Monoclonal |
WB
EL
ICC
IHC
|
 Atlas Antibodies |
HPA003254 |
0 references | Polyclonal |
WB
IHC
|
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