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Protein structure
IRF3
Interferon regulatory factor 3This gene encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes. The protein plays an important role in the innate immune response against DNA and RNA viruses. Mutations in this gene are associated with Encephalopathy, acute, infection-induced, herpes-specific, 7. [provided by RefSeq, Sep 2020]
Top validated antibodies |
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| Proteintech Group |  11312-1-AP |
73 references | Polyclonal |
WB
EL
ICC
IP
IHC
FC
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| Invitrogen Antibodies | 11312-1-AP |
Polyclonal |
WB
ICC
IP
IHC
FC
OA
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| antibodies-online | ABIN2668744 |
Polyclonal |
WB
ICC
IP
IHC
FC
ChIP
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| NSJ Bioreagents | RQ5692 |
Polyclonal |
WB
EL
ICC
IHC
FC
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| NovoPro Bioscience Inc. | 111835 |
Polyclonal |
WB
EL
ICC
IP
IHC
FC
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