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Cell line expression
Protein structure
NPM1
Nucleophosmin 1B23, NPM
The protein encoded by this gene is involved in several cellular processes, including centrosome duplication, protein chaperoning, and cell proliferation. The encoded phosphoprotein shuttles between the nucleolus, nucleus, and cytoplasm, chaperoning ribosomal proteins and core histones from the nucleus to the cytoplasm. This protein is also known to sequester the tumor suppressor ARF in the nucleolus, protecting it from degradation until it is needed. Mutations in this gene are associated with acute myeloid leukemia. Dozens of pseudogenes of this gene have been identified. [provided by RefSeq, Aug 2017]
Top validated antibodies |
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| Invitrogen Antibodies |  32-5200 |
101 references | Monoclonal |
WB
EL
ICC
IP
IHC
FC
OA
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| Proteintech Group | 10306-1-AP |
15 references | Polyclonal |
WB
EL
ICC
IP
IHC
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| Abnova Corporation | H00004869-M01 |
1 references | Monoclonal |
WB
EL
ICC
IHC
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| Novus Biologicals | NB110-61646 |
1 references | Polyclonal |
WB
ICC
IP
IHC
FC
|
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| NSJ Bioreagents | V7981 |
Monoclonal |
WB
ICC
IHC
FC
OA
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