Explore
Validate
LearnTissue expression
Cell line expression
Protein structure
POU5F1
POU class 5 homeobox 1MGC22487, OCT3, Oct4, OTF3
This gene encodes a transcription factor containing a POU homeodomain that plays a key role in embryonic development and stem cell pluripotency. Aberrant expression of this gene in adult tissues is associated with tumorigenesis. This gene can participate in a translocation with the Ewing's sarcoma gene on chromosome 21, which also leads to tumor formation. Alternative splicing, as well as usage of alternative AUG and non-AUG translation initiation codons, results in multiple isoforms. One of the AUG start codons is polymorphic in human populations. Related pseudogenes have been identified on chromosomes 1, 3, 8, 10, and 12. [provided by RefSeq, Oct 2013]
Top validated antibodies |
|||||
| Invitrogen Antibodies |  701756 |
5 references | Monoclonal |
WB
ICC
FC
ChIP
OA
|
|
| GeneTex | GTX101497 |
10 references | Polyclonal |
WB
ICC
IP
IHC
FC
|
|
| Proteintech Group | 11263-1-AP |
134 references | Polyclonal |
WB
EL
ICC
IHC
|
|
| R&D Systems | AF1759 |
23 references | Polyclonal |
WB
ICC
IP
ChIP
|
|
| Novus Biologicals | AF1759 |
25 references | Polyclonal |
WB
ICC
IP
ChIP
|
|
All Antibodies
Filters
Enhanced validation Supportive data in Antibodypedia Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider