Tissue expression
Cell line expression

TJP1

gene product
DKFZp686M05161, MGC133289, ZO-1 
This gene encodes a member of the membrane-associated guanylate kinase (MAGUK) family of proteins, and acts as a tight junction adaptor protein that also regulates adherens junctions. Tight junctions regulate the movement of ions and macromolecules between endothelial and epithelial cells. The multidomain structure of this scaffold protein, including a postsynaptic density 95/disc-large/zona occludens (PDZ) domain, a Src homology (SH3) domain, a guanylate kinase (GuK) domain and unique (U) motifs all help to co-ordinate binding of transmembrane proteins, cytosolic proteins, and F-actin, which are required for tight junction function. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2017]
More gene data

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435 antibodies from 41 providers.

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AntibodyRefsTypeWBELICCIPIHCFC
GeneTex
7 antibodies
Proteintech Group
3 antibodies
Invitrogen Antibodies
18 antibodies
NovoPro Bioscience Inc.
2 antibodies
Wuhan Fine Biotech Co., Ltd.
2 antibodies
Novus Biologicals
6 antibodies
antibodies-online
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Atlas Antibodies
2 antibodies
NSJ Bioreagents
6 antibodies
SICGEN
1 antibody
Boster Biological Technology
3 antibodies
OriGene
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LifeSpan BioSciences, Inc.
98 antibodies
Aviva Systems Biology
6 antibodies
Affinity Biosciences
2 antibodies
Bethyl Laboratories
2 antibodies
Rockland Immunochemicals, Inc.
2 antibodies
Biorbyt
37 antibodies
Cell Signaling Technology, Inc
3 antibodies
St John's Laboratory
5 antibodies
Arigo
4 antibodies
Abnova Corporation
6 antibodies
ProSci
2 antibodies
Signalway Antibody LLC
2 antibodies
Cusabio Biotech Co., Ltd
8 antibodies
Creative Biolabs
15 antibodies
Creative Diagnostics
6 antibodies
Abbkine Scientific Co.Ltd.
1 antibody
Antibodies.com
1 antibody
HUABIO Research
1 antibody
Acris Antibodies GmbH
5 antibodies
Everest Biotech
1 antibody
Abgent
3 antibodies
MyBioSource
10 antibodies
United States Biological
26 antibodies
EMD Millipore
2 antibodies
Abbexa
5 antibodies
Abiocode, Inc.
1 antibody
RabMAbs
1 antibody
MilliporeSigma / Merck KGaA
3 antibodies