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LearnTissue expression
Cell line expression
Protein structure
LEF1
Lymphoid enhancer binding factor 1TCF10, TCF1ALPHA, TCF7L3
This gene encodes a transcription factor belonging to a family of proteins that share homology with the high mobility group protein-1. The protein encoded by this gene can bind to a functionally important site in the T-cell receptor-alpha enhancer, thereby conferring maximal enhancer activity. This transcription factor is involved in the Wnt signaling pathway, and it may function in hair cell differentiation and follicle morphogenesis. Mutations in this gene have been found in somatic sebaceous tumors. This gene has also been linked to other cancers, including androgen-independent prostate cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]
Top validated antibodies |
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| Novus Biologicals |  H00051176-M01 |
3 references | Monoclonal |
WB
EL
ICC
BN
PLA
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| Proteintech Group | 14972-1-AP |
17 references | Polyclonal |
WB
EL
IP
IHC
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| Atlas Antibodies | HPA002087 |
1 references | Polyclonal |
WB
ICC
IHC
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| Invitrogen Antibodies | PA5-82000 |
1 references | Polyclonal |
WB
ICC
IHC
OA
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| antibodies-online | ABIN395469 |
Monoclonal |
WB
EL
ICC
IHC
|
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