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LearnTissue expression
Cell line expression
Protein structure
CDK1
Cyclin dependent kinase 1CDC2, CDC28A
The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF), which is essential for G1/S and G2/M phase transitions of eukaryotic cell cycle. Mitotic cyclins stably associate with this protein and function as regulatory subunits. The kinase activity of this protein is controlled by cyclin accumulation and destruction through the cell cycle. The phosphorylation and dephosphorylation of this protein also play important regulatory roles in cell cycle control. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
Top validated antibodies |
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| Proteintech Group |  19532-1-AP |
103 references | Polyclonal |
WB
EL
ICC
IHC
FC
|
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| Invitrogen Antibodies | 33-1800 |
10 references | Monoclonal |
WB
EL
IP
IHC
FC
OA
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| antibodies-online | ABIN393442 |
5 references | Monoclonal |
WB
EL
ICC
IHC
|
|
| GeneTex | GTX108120 |
10 references | Polyclonal |
WB
ICC
IP
IHC
|
|
| Novus Biologicals | NBP2-34711-0.1 mg |
Monoclonal |
WB
EL
ICC
IP
IHC
FC
|
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